I don’t know everything, but I can help to answer questions about PHP / Bootstrap, JS, etc.
Recently I’ve been working on a repeatable recipe to install Nginx, several PHP versions, and Let’s Encrypt on top of Debian Linux. Currently I have PHP 7.4, 8.0, 8.1, and 8.2 installed. Each Web App can use any of the installed versions.
Previously, I’ve used Bitnami LEMP which has everything already installed, but it does not seem to be a good idea, from what I’ve read, to upgrade php on Bitnami LEMP.
I really do not like the idea of having to spin up another instance just to upgrade PHP. By installing everything on top of a clean Debian Linux, it’s simple to add/install new versions of PHP. And if things go wonky, reinstalling is still an option.